Metabonomics study of the therapeutic mechanism of fenugreek galactomannan on diabetic hyperglycemia in rats, by ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry
文摘
UPLC-QTOF/MS-based metabonomics approach was applied to study the therapeutic mechanism underlying F-GAL in diabetes. Fourteen potential biomarkers were identified. Such as urocanic acid, citric acid, hippuric acid, arachidonic acid, and so on. F-GAL was elucidated to be a potential therapeutic agent for the treatment of diabetes via multiple therapeutic mechanisms.