Spatial cognition following early-life seizures in rats: Performance deficits are dependent on task demands
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- 作者：Jeremy M. Barry ; Jeremy.Barry@med.uvm.edu" class="auth_mail" title="E-mail the corresponding author ; Chengju Tian ; Anthony Spinella ; Matias Page ; Gregory L. Holmes
- 关键词：Epilepsy ; Morris water maze ; Active avoidance ; Epilepsy ; Myelin
- 刊名：Epilepsy & Behavior
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：60
- 期：Complete
- 页码：1-6
- 全文大小：941 K
文摘
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We did not find MWM task spatial deficits in 6-month-old ELS animals.
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ELS animals exhibited performance deficits on an active avoidance task.
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ELS animals accrued more shocks than controls on the second training day.
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ELS animals tended to do worse than controls on later training trials each day.
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Performance deficits are not due to alterations in white matter integrity.