• 作者：Walter Alberto Sifuentes Giraldo ; Mar¨ªa Luz G¨¢mir G¨¢mir
• 关键词：Espondiloartritis juvenil ; Espondilitis anquilosante juvenil ; Artritis relacionada con entesitis
• 刊名：Seminarios de la Fundaci¨®n Espa?ola de Reumatolog¨ªa
• 出版年：2013
• 出版时间：October-December, 2013
• 年：2013
• 卷：14
• 期：4
• 页码：106-120
• 全文大小：2597 K

Juvenile-onset spondyloarthritis is a special group within the entities included in the concept of spondyloarthritis, and is characterized by a predominantly peripheral involvement (arthritis and enthesitis), and more frequent presentation as undifferentiated forms. However, like its adult-onset equivalent, it has the potential to develop structural damage and progress to juvenile ankylosing spondylitis, with consequent irreversible functional impairment. Many important advances have been made in the understanding of the genetics and pathophysiology of juvenile-onset spondyloarthritis, as well as in the diagnosis and treatment of this entity. These advances are summarized in this article.