Molecular targets of quercetin with anti-inflammatory properties in atopic dermatitis
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- 作者：Vengadeshprabhu Karuppagounder1 ; vengadeshprabu@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Somasundaram Arumugam1 ; Rajarajan A. Thandavarayan2 ; Remya Sreedhar1 ; Vijayasree V. Giridharan3 ; Kenichi Watanabe1 ; watanabe@nupals.ac.jp" class="auth_mail" title="E-mail the corresponding author
- 刊名：Drug Discovery Today
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：21
- 期：4
- 页码：632-639
- 全文大小：2359 K
文摘
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Atopic dermatitis (AD) is a chronic inflammatory skin disease.
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Multiple signaling pathways may combine to produce pathological changes in AD.
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Quercetin is a potent pleiotropic molecule that regulates multiple pathways.
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Quercetin bioavailability limits its usage in clinical settings.
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Various approaches to improve quercetin pharmacokinetics are addressed.