Integrated analysis neurimmiRs of tilapia (Oreochromis niloticus) involved in immune response to Streptococcus agalactiae, a pathogen causing meningoencephalitis in teleosts
Five Oreochromis niloticus brain sRNA libraries were constructed and deep sequenced. A total of 486 conserved and 1954 novel miRNAs were identified. 547 miRNAs were differentially expressed among in five libraries. Selected miRNA expression levels were consistent between sequencing and qPCR data. Annotation of targets revealed a broad range of signal pathways.