Palladium mediated activation of C–F bonds in 2,4,6-trifluoropyrimidine: Synthesis and structure of palladium pyrimidyloxy and pyrimidinone derivatives

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• 作者：Thomas Braun ; Verena Schorlemer ; Beate Neumann and Hans-Georg Stammler
• 关键词：Palladium ; Binuclear compounds ; Fluorinated heterocycles ; C– ; F activation
• 刊名：Journal of Fluorine Chemistry
• 出版年：2006
• 出版时间：March 2006
• 年：2006
• 卷：127
• 期：3
• 页码：367-372
• 全文大小：230 K

文摘

[PdMe₂(dcpm)] (1) reacts with 2,4,6-trifluoropyrimidine in the presence of water to give the palladium derivative [PdMe{4-C₄N₂F₂H(O)}(dcpm)] (2). When additional triethylamine is present complex [PdMe(2-OC₄N₂F₂H)(dcpm)] (4) in addition to 2 is formed. Compound 2 converts slowly into the binuclear complex [Pd{4-C₄N₂F₂H(O)}(μ-dcpm)]₂ (5). The molecular structure of 5 was determined by X-ray crystallography. The palladium–palladium distance is 2.5898(3) Å.