Dinuclear Rh(II) complexes with one polypyridyl ligand, structure, properties and antitumor activity

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• 作者：Magdalena Ć ; wikowska ; Florian P. Pruchnik ; Radosł ; aw Starosta ; Henryk Chojnacki ; Adam Wilczok ; Stanisł ; aw Uł ; aszewski
• 关键词：Rhodium(II) ; Dinuclear rhodium complexes ; Polypyridyls ; Antitumor activity ; DFT calculation ; UV– ; Vis spectra
• 刊名：Inorganica Chimica Acta
• 出版年：2010
• 出版时间：10 August 2010
• 年：2010
• 卷：363
• 期：11
• 页码：2401-2408
• 全文大小：435 K

文摘

Rhodium(II) complexes [Rh₂(μ-OAc)₂(OAc)(bpy)(H₂O)₂]PF₆ (1), [Rh₂(μ-OAc)₂(OAc)(phen)(H₂O)₂](PF₆)·H₂O (2), [Rh₂(μ-OOCCH₃)₃(OOCCH₃)(phen)] (3) and [Rh₂(μ-O₂CCH₃)₃(O₂CCH₃)(Ph₂phen)] (4) (Ph₂phen = 4,7-diphenyl-1,10-phenanthroline) have been synthesized and characterized by means of NMR, IR and UV–Vis spectroscopic methods. X-ray structure of complex 4·1.5(CH₃COCH₃) has been determined and its geometry and electronic structure has been elucidated using OPBE and B3LYP DFT methods. The compounds are active cytostatic agents against tumor cells.