Dopamine Neuron-Specific Optogenetic Stimulation in Rhesus Macaques
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- 作者：William R. Stauffer1 ; 3 ; 5 ; wrs@pitt.edu" class="auth_mail" title="E-mail the corresponding author ; Armin Lak1 ; 4 ; Aimei Yang2 ; Melodie Borel1 ; Ole Paulsen1 ; Edward S. Boyden2 ; Wolfram Schultz1
- 刊名：Cell
- 出版年：2016
- 出版时间：8 September 2016
- 年：2016
- 卷：166
- 期：6
- 页码：1564-1571.e6
- 全文大小：2745 K
文摘
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Cell-type-specific promoter drives Cre-dependent ChR2 expression in monkey
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Optogenetically activated neurons had dopamine-like features and reward responses
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Dopamine neurons respond strongly to cues predicting optical stimulation
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Monkeys choose predicted optogenetic stimulation over no predicted stimulation