Stanniocalcin 2 promotes cell proliferation and cisplatin resistance in cervical cancer
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- 作者：Yuxia Wanga ; Ying Gaoa ; Hairong Chenga ; Guichun Yanga ; Wenhua Tanb ; tanwenhua1962@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Stanniocalcin 2 ; Cervical cancer ; Cisplatin ; Proliferation ; Apoptosis ; MAPK
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2015
- 出版时间：23 October 2015
- 年：2015
- 卷：466
- 期：3
- 页码：362-368
- 全文大小：1491 K
文摘
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STC2 was upregulated in cervical cancer and promoted cervical cancer cell proliferation.
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Cisplatin resistant cells had elevated STC2 levels and enhanced proliferation.
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STC2 regulated cisplatin chemosensitivity in cervical cancer cells.
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STC2 regulated the activity of the MAPK signaling pathway.