Slowed peak resting frequency and MEG overactivation in survivors of severe sepsis and septic shock
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- 作者：Theresa Gö ; tza ; b ; 1 ; theresa@biomag.uni-jena.de" class="auth_mail" title="E-mail the corresponding author ; Philipp Baumbacha ; b ; c ; 1 ; Philipp.Baumbach@med.uni-jena.de" class="auth_mail" title="E-mail the corresponding author ; Ralph Huonkera ; b ; rhuonker@biomag.uni-jena.de" class="auth_mail" title="E-mail the corresponding author ; Cornelia Kranczioche ; f ; cornelia.kranczioch@uni-oldenburg.de" class="auth_mail" title="E-mail the corresponding author ; Otto W. Wittea ; g ; otto.witte@med.uni-jena.de" class="auth_mail" title="E-mail the corresponding author ; Stefan Debenere ; f ; stefan.debener@uni-oldenburg.de" class="auth_mail" title="E-mail the corresponding author ; Carsten Klingnera ; g ; carsten.klingner@med.uni-jena.de" class="auth_mail" title="E-mail the corresponding author ; Frank M. Brunkhorstd ; Frank.Brunkhorst@med.uni-jena.de" class="auth_mail" title="E-mail the corresponding author ; Albrecht Gü ; ntherg ; albrecht.guenther@med.uni-jena.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：Long-term cognitive impairments ; Magnetoencephalography ; Neuronal oscillations ; Resting activity ; Sepsis
- 刊名：Clinical Neurophysiology
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：127
- 期：2
- 页码：1247-1253
- 全文大小：705 K
文摘
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In survivors of severe sepsis and septic shock, resting (alpha) frequency, which was closely correlated with mental status, decreased towards the theta range, but increases to the level of healthy controls within one year after sepsis.
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Spectral alpha power in sepsis survivors exceeded the power in healthy controls, but did not decrease with time.
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The postseptic frequency shift might be due to abnormal thalamocortical dynamics.