Association of lectin pathway proteins with intra-abdominal Candida infection in high-risk surgical intensive-care unit patients. A prospective cohort study within the fungal infection network of Switzerland
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- 作者：Michael Osthoffa ; b ; g ; michael.osthoff@usb.ch" class="auth_mail" title="E-mail the corresponding author ; Agnieszka Wojtowiczc ; g ; Frederic Tissotc ; Clara Jø ; rgensend ; Steffen Thield ; Stephan Zimmerlie ; Oscar Marchettic ; Nina Khannaa ; b ; Pierre-Yves Bochudc ; Marten Trendelenburgb ; f ; the Fungal Infection Network of Switzerland (FUNGINOS)h ; Thomas Bregenzer ; Anna Conen ; Hans Fankhauser ; Ursula Flü ; ckiger ; Nina Khanna ; Reno Frei ; Ulrich Heininger ; Roland Hertel ; Mario Franciolli ; Ospedale San Giovanni ; Marisa Dolina ; Madeleine Rothen ; Olivier Dubuis ; Philipp Tarr ; Suzanne Graf ; Felix Fleisch ; Martin Risch ; Eva Ritzler ; Christian Chuard ; Vé ; ronique Erard ; Dominique Fracheboud ; Sté ; phane Emonet ; Daniel Genne ; Reto Lienhardt ; Jean-Philippe Chave ; Corinne Andreutti-Zaugg ; Alberto Gallusser ; Peter Graber ; Rita Monotti ; Enos Bernasconi ; Martin Krause ; Karin Herzog ; Rein-Jan Piso ; Urs Schibli ; Frank Bally ; Nicolas Troillet ; Lysiane Tissiè ; re ; Katja Boggian ; Thomas Bruderer ; Jacques Gubler ; Gerhard Eich ; Christoph Berger
- 关键词：Complement system ; Mannose-binding lectin ; Ficolins ; Candida infections ; Intensive-care unit
- 刊名：Journal of Infection
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：72
- 期：3
- 页码：377-385
- 全文大小：580 K
文摘
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Mannose-binding lectin has been shown to bind to Candida albicans.
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Lectin complement proteins were evaluated in high-risk intensive-care unit patients.
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Lectin protein levels were not associated with Candida colonization or infection.
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Mannose-binding lectin genotype was not associated with Candida infection.