Human hepatic stellate cells and inflammation: A regulated cytokine network balance

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• 作者：Mehdi Najar^a ; ¹ ; ^{mnajar@ulb.ac.be} ; Hussein Fayyad-Kazan^b ; ¹ ; Wissam H. Faour^c ; Adil El Taghdouini^e ; Gordana Raicevic^a ; Mustapha Najimi^d ; Michel Toungouz^a ; Leo A. van Grunsven^e ; Etienne Sokal^d ; Laurence Lagneaux^a
• 关键词：Hepatic stellate cells ; Inflammation ; Immunological cytokine profile ; Immune response balance ; Liver cell therapy
• 刊名：Cytokine
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：90
• 期：Complete
• 页码：130-134
• 全文大小：790 K
• 卷排序：90

文摘

Inflammation alters the immunological shape of HSCs. A shift in the cytokine profile of HSCs toward a more pro-inflammatory one is observed. The induction of pro inflammatory cytokines could thus have important implications for the liver immune response.