Adipose Snail1 Regulates Lipolysis and Lipid Partitioning by Suppressing Adipose Triacylglycerol Lipase Expression

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• 作者：Chengxin Sun¹ ; ² ; ⁵ ; Lin Jiang² ; ⁵ ; Yan Liu² ; Hong Shen² ; Stephen J. Weiss³ ; ⁴ ; Yifa Zhou¹ ; ^{zhouyf383@nenu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Liangyou Rui² ; ⁴ ; ⁶ ; ^{ruily@umich.edu" class="auth_mail" title="E-mail the corresponding author}
• 关键词：obesity ; insulin resistance ; type 2 diabetes ; liver steatosis ; NAFLD ; lipolysis ; adipocytes ; hepatocytes ; Snail1 ; ATGL
• 刊名：Cell Reports
• 出版年：2016
• 出版时间：15 November 2016
• 年：2016
• 卷：17
• 期：8
• 页码：2015-2027
• 全文大小：4368 K

文摘

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d="p0010">Insulin increases Snail1 levels in white adipocytes

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d="p0015">Snail1 represses ATGL expression and suppresses lipolysis

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d="p0020">Adipocyte-specific deletion of Snail1 decreases adipocyte size and adiposity

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d="p0025">Adipocyte-specific deletion of Snail1 promotes liver steatosis in mice

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