The Relationship Between Two Performance Scales: New York Heart Association Classification and Karnofsky Performance Status Scale

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• 作者：Miriam J. Johnson ; MD^a ; ^{miriam.johnson@hyms.ac.uk" class="auth_mail} ; J. Martin Bland ; PhD^b ; Patricia M. Davidson ; PhD^c ; Phillip J. Newton ; PhD^c ; Stephen G. Oxberry ; PhD^d ; Amy P. Abernethy ; MD^e ; ^f ; David C. Currow ; FRACP^f
• 关键词：Performance status ; Karnofsky Performance Status Scale ; New York Heart Association Classification
• 刊名：Journal of Pain and Symptom Management
• 出版年：March, 2014
• 年：2014
• 卷：47
• 期：3
• 页码：652-658
• 全文大小：161 K

文摘

Context

Performance status is used to quantify the well-being and functional status of people with illness. Clinicians and researchers from differing fields may not instinctively understand the scales, typically disease specific, used in other disciplines.

Objectives

To provide a preliminary description of the relationship between the Karnofsky Performance Status Scale (KPS) and the New York Heart Association Classification (NYHA) and to stimulate discussion in research and clinical practice.

Methods

Simultaneous KPS and NYHA data (172 observations) from three studies of people with chronic heart failure were pooled. Linear regression was used to predict the mean KPS from NYHA. The strength of association between the scales was investigated using a Kendall's Tau-b correlation coefficient. The agreement between the predicted and observed KPS scores was investigated using weighted kappa with quadratic weights.

Results

Linear regression demonstrated a relationship between KPS and NYHA (P聽<聽0.0001; R²聽=聽0.3). Predicted KPS from NYHA class rounded to the nearest 10 gave the following values: Class I, predicted KPS 90%; Class II, predicted KPS 80%; Class III, predicted KPS 70%; and Class IV, predicted KPS 60%. A moderate strength of association between KPS and NYHA (Kendall's Tau-b correlation coefficient of 鈭?.49; P聽<聽0.0001) and agreement between observed and predicted KPS (kappa coefficient聽=聽0.52) was shown.

Conclusion

We suggest that the NYHA discriminates poorly between clinically聽important performance states in people with advanced disease (NYHA III and IV; KPS <50%). The KPS, used in conjunction, would provide useful additional information in research and clinical practice.