Purpose: To determine the frequency of, and factors associated with, EUS findings consistent with the ventral anlage.
Methods: One hundred patients undergoing upper gastrointestinal EUS for any indication were prospectively evaluated for the presence of a focal, hypoechoic area in the pancreatic head using a radial scanning echoendoscope. Multiple clinical and EUS variables were tested against the ability to detect the ventral anlage.
Results: The overall detection rate of the ventral anlage was 59 % . The ventral anlage was detected in 75 % of patients undergoing EUS for nonpancreatic indications, compared to 40 % of patients undergoing EUS to evaluate suspected pancreatic disease (p<0.001). EUS detected the ventral anlage in 72 % of patients with a normal EUS-appearing pancreatic head, compared to 29 % of patients who had abnormal pancreatic head parenchyma (mass or chronic pancreatitis) on EUS (p<0.001). Multivariate analysis revealed the only variable associated with detecting the ventral anlage was abnormal pancreatic head parenchyma on EUS.
Conclusion: The ventral anlage is frequently detected during pancreatic EUS, with a significantly lower rate of detection in patients with EUS findings of a pancreatic head mass or diffuse chronic pancreatitis.