Electronic Alerts, Comparative Practitioner Metrics, and Education Improves Thromboprophylaxis and Reduces Thrombosis

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• 作者：Scott C. Woller ; MD^a ; ^b ; ^{scott.woller@imail.org" class="auth_mail" title="E-mail the corresponding author} ; Scott M. Stevens ; MD^a ; ^b ; R. Scott Evans ; PhD^c ; ^d ; Daniel G. Wray ; MS ; MBA^e ; John C. Christensen ; MD^a ; ^b ; Valerie T. Aston ; BS^a ; Matthew H. Wayne ; MBA^f ; James F. Lloyd ; BS^c ; Emily L. Wilson ; MS^g ; C. Gregory Elliott ; MD^a ; ^b
• 关键词：Chemoprophylaxis medical patient ; Prevention ; Quality improvement ; Venous thromboembolism
• 刊名：The American Journal of Medicine
• 出版年：2016
• 出版时间：October 2016
• 年：2016
• 卷：129
• 期：10
• 页码：1124.e17-1124.e26
• 全文大小：754 K

文摘

Venous thromboembolism chemoprophylaxis remains underutilized in hospitalized medical patients at high risk for venous thromboembolism. We assessed the effect of a health care quality-improvement initiative comprised of a targeted electronic alert, comparative practitioner metrics, and practitioner-specific continuing medical education on the rate of appropriate venous thromboembolism chemoprophylaxis provided to medical inpatients at high risk for venous thromboembolism.

Methods

We performed a multicenter prospective observational cohort study in an urban Utah hospital system. All medical patients admitted to 1 of 2 participating hospitals from April 1, 2010 to December 31, 2012 were eligible. Patients were members of the “control” (April 1, 2010 to December 31, 2010), “intervention” (January 1, 2011 to December 31, 2011), or “subsequent year” (January 1, 2012 to December 31, 2012) group. The primary outcome was the rate of appropriate chemoprophylaxis among patients at high risk for venous thromboembolism. Secondary outcomes included rates of symptomatic venous thromboembolism, major bleeding, all-cause mortality, heparin-induced thrombocytopenia, physician satisfaction, and alert fatigue.

Results

The rate of appropriate chemoprophylaxis among patients at high risk for venous thromboembolism increased (66.1% control period vs 81.0% intervention period vs 88.1% subsequent year; P <.001 for each comparison). A significant reduction of 90-day symptomatic venous thromboembolism accompanied the quality initiative (9.3% control period, 9.7% intervention period, 6.7% subsequent year; P = .009); 30-day venous thromboembolism rates also significantly decreased.

Conclusions

A multifaceted intervention was associated with increased appropriate venous thromboembolism chemoprophylaxis among medical inpatients at high risk for venous thromboembolism and reduced symptomatic venous thromboembolism. The effect of the intervention was sustained.