Biological actions and molecular effects of resveratrol, pterostilbene, and 3′-hydroxypterostilbene

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• 作者：Hui-Yun Tsai^a ; Chi-Tang Ho^a ; ^{ho@aesop.rutgers.edu} ; Yu-Kuo Chen^b ; ^{chenyk@mail.npust.edu.tw}
• 关键词：3&prime ; -hydroxypterostilbene ; bioavailability ; biological actions ; pterostilbene ; resveratrol ; stilbenes
• 刊名：Journal of Food and Drug Analysis
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：25
• 期：1
• 页码：134-147
• 全文大小：449 K
• 卷排序：25

文摘

Stilbenes are a class of polyphenolic compounds, naturally found in a wide variety of dietary sources such as grapes, berries, peanuts, red wine, and some medicinal plants. There are several well-known stilbenes including trans-resveratrol, pterostilbene, and 3′-hydroxypterostilbene. The core chemical structure of stilbene compounds is 1,2-diphenylethylene. Recently, stilbenes have attracted extensive attention and interest due to their wide range of health-beneficial effects such as anti-inflammation, -carcinogenic, -diabetes, and -dyslipidemia activities. Moreover, accumulating in vitro and in vivo studies have reported that stilbene compounds act as inducers of multiple cell-death pathways such as apoptosis, cell cycle arrest, and autophagy for chemopreventive and chemotherapeutic agents in several types of cancer cells. The aim of this review is to highlight recent molecular findings and biological actions of trans-resveratrol, pterostilbene, and 3′-hydroxypterostilbene.