g class="boldFont">Backgroundg>: New strategies that promote clearance of excess cholesterol by reverse cholesterol transport (RCT) are needed.
g class="boldFont">Resultsg>: SOF promotion of hepatic CE uptake, metabolism and secretion as bile acids in vitro and in vivo was investigated.
g class="boldFont">Conclusiong>: Both in vitro and in vivo, CERM-CE is metabolized by hepatocytes to bile acids and secreted.
g class="boldFont">Significanceg>: The SOF product CERM delivers cholesterol to the liver, supporting it as a therapeutic strategy to promote RCT.
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