刊名:Biochemical and Biophysical Research Communications
出版年:2017
出版时间:22 January 2017
年:2017
卷:482
期:4
页码:902-908
全文大小:1346 K
卷排序:482
文摘
CYP107L2 from S. avermitilis shares a high sequence similarity with the PikC. Purified CYP107L2 yielded a typical type I binding spectra to pikromycin and lauric acid. Crystal structure of CYP107L2 complex with lauric acid was determined at 2.5 Å resolution. Laurate is bound mainly via hydrophobic interactions in the substrate binding cavity of CYP107L2.