Validation of QuickDASH Outcome Measure in Breast Cancer Survivors for Upper Extremity Disability

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• 作者：Mously LeBlanc ; MD^a ; ^c ; ^{mously.leblanc@uphs.upenn.edu" class="auth_mail" title="E-mail the corresponding author} ; Margaret Stineman ; MD^a ; ^b ; Angela DeMichele ; MD ; MSCE^b ; ^c ; Carrie Stricker ; PhD ; RN^c ; Jun J. Mao ; MD ; MSCE^b ; ^c ; ^d
• 关键词：Breast neoplasms ; Disability evaluation ; Rehabilitation ; Upper extremity ; Validation studies
• 刊名：Archives of Physical Medicine and Rehabilitation
• 出版年：2014
• 出版时间：March 2014
• 年：2014
• 卷：95
• 期：3
• 页码：493-498
• 全文大小：240 K

文摘

To validate the QuickDASH as a patient-reported outcome measure for assessing upper extremity disability in breast cancer survivors.

Design

Large cross-sectional survey.

Setting

Ambulatory care center at a university hospital.

Participants

Postmenopausal women (N=150) with stage I to III hormone receptor–positive breast cancer currently taking a third-generation aromatase inhibitor.

Interventions

Not applicable.

Main Outcome Measure

QuickDASH, an 11-item self-administered questionnaire, assesses global arm function over the past 7 days.

Results

Of 150 surveys, 148 (99%) were scorable. The factor analysis demonstrated 1 factor with an eigenvalue of 6.7, which explains 61% of variance. The score was reliable with a Cronbach alpha of .93. The test-retest reliability was .78 over 2 weeks. The mean QuickDASH score ± SD for all patients was 19±19. Those with upper extremity arthralgias reported higher QuickDASH scores than controls without pain (26 vs 12, P=.001). Those with frozen shoulder pain also reported higher QuickDASH scores than controls without pain (37 vs 15, P=.001).

Conclusions

The QuickDASH instrument is a convenient, reliable, and valid patient-reported outcome measure to assess upper extremity disability in patients with breast cancer.