Structure prediction and network analysis of chitinases from the Cape sundew, Drosera capensis

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• 作者：Megha H. Unhelkar^a ; ¹ ; Vy T. Duong^a ; ^b ; ¹ ; Kaosoluchi N. Enendu^b ; John E. Kelly^a ; Seemal Tahir^a ; Carter T. Butts^c ; ^d ; ^e ; ^{buttsc@uci.edu} ; Rachel W. Martin^a ; ^b ; ^{rwmartin@uci.edu}
• 关键词：Chitinase ; Protein sequence analysis ; Protein structure prediction ; Protein structure network ; Molecular dynamics ; In silico maturation
• 刊名：Biochimica et Biophysica Acta (BBA) - General Subjects
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：1861
• 期：3
• 页码：636-643
• 全文大小：2485 K
• 卷排序：1861

文摘

We report eleven new chitinases from the carnivorous plant Drosera capensis. A novel two domain class IV chitinase similar to those found in microbes was found. Protein structure prediction and comparison to other carnivorous plant chitinases reveals commonalities. Sequence and structural motifs are conserved among carnivorous plant chitinases. Protein structure networks reveal structural differences and predict functionality.