Structural equation modeling identifies markers of damage and function in the aging male Fischer 344 rat
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- 作者：Elizabeth A. Grunz-Borgmanna ; LaNita A. Nicholsa ; Charles E. Wiedmeyerb ; Sean Spagnolic ; Jerome P. Trzeciakowskid ; Alan R. Parrisha ; parrishar@health.missouri.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Aging ; Kim-1 ; Proteinuria ; Structural equation modeling
- 刊名：Mechanisms of Ageing and Development
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：156
- 期：Complete
- 页码：55-62
- 全文大小：1693 K
文摘
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Changes in renal structure and function begin as early as 16 months in the male Fischer 344 rat.
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Proteinuria and urinary Kim-1 are predictors of age-related changes in renal structure and function.
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Structural equation modeling can discriminate factors associated with either Damage or Function.