Molecular structure and function of P2X receptors
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- 作者：Chloé ; Habermachera ; b ; Kate Dunninga ; b ; Thierry Chataigneaua ; b ; Thomas Gruttera ; b ; grutter@unistra.fr" class="auth_mail" title="E-mail the corresponding author
- 关键词：ATP ; Gating ; Ion channel ; Purinergic receptors ; Allosteric modulation
- 刊名：Neuropharmacology
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：104
- 期：Complete
- 页码：18-30
- 全文大小：2253 K
文摘
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ATP-gated P2X receptors are trimeric ion channels involved in neuronal signalling.
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Principles of ligand binding and molecular gating in P2X receptors are explored.
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Principles of allosteric modulation with regards to P2X receptors are explored.
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Recent developments of light-gated P2X ion channels are discussed.