Kinetic parameters have been estimated for the degradation that could be described by first-order kinetics. At temperatures below 110 °C indole glucosinolates have a significant higher degradation rate constant as compared to aliphatic glucosinolates. The breakdown of 4-hydroxyglucobrassicin seems to consist of two parallel reaction pathways. Based on the proposed degradation kinetics and the estimated parameters, the degree of thermal degradation of all individual glucosinolates at standardized heating conditions (blanching, cooking and canning) was simulated. Glucosinolates are expected to be not very susceptible to thermal degradation during blanching conditions. Cooking will cause more thermal degradation to indole glucosinolates (38 % ) as compared to aliphatic glucosinolates (8 % ). Canning, the most severe heat treatment, will result in significant thermal degradation (73 % ) of the total amount of glucosinolates.