Oral subchronic exposure to silver nanoparticles in rats
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- 作者：Tania Garciaa ; c ; Daisy Lafuentea ; b ; Jordi Blancoa ; b ; Domè ; nec J. Sá ; ncheza ; b ; Juan J. Sirventd ; José ; L. Domingoa ; Mercedes Gó ; meza ; c ; mariamercedes.gomez@urv.cat" class="auth_mail" title="E-mail the corresponding author
- 关键词：Silver nanoparticles ; Rats ; Oral exposure ; Metals
- 刊名：Food and Chemical Toxicology
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：92
- 期：Complete
- 页码：177-187
- 全文大小：2150 K
文摘
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We investigated in rats the potential toxic effects of oral PVP-AgNPs.
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After 90 days of treatment, AgNPs were found within hepatic and ileum cells.
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No harmful effects in liver and kidney, as well as in biochemical markers were noted at any treatment dose.
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PVP-AgNPs could alter Zn and Cu levels in thymus and brain of treated animals.