GABAergic modulation of serotonin release in the rat subfornical organ area
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- 作者：Makoto Takahashi ; Dr.a ; Masahiko Nomura ; Dr.c ; Junichi Tanaka ; Dr.a ; b ; tanakaj@naruto-u.ac.jp" class="auth_mail" title="E-mail the corresponding author
- 关键词：Subfornical organ ; Serotonin ; γ&ndash ; aminobutyric acid ; Hypovolemia
- 刊名：Neuroscience Letters
- 出版年：2016
- 出版时间：6 September 2016
- 年：2016
- 卷：630
- 期：Complete
- 页码：114-119
- 全文大小：1428 K
文摘
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Perfusion with the GABAA antagonist through a microdialysis probe enhances 5-HT in the SFO.
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Higher perfusion with the GABAA or GABAB agonist reduces the 5-HT levels.
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The GABAA agonist attenuates the hypovolemia-increase in the 5-HT.
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Muscimol, but not baclofen, affects in the 5-HT-mediated body fluid balance in the SFO.