Whole genome sequencing of diverse Shiga toxin-producing and non-producing Escherichia coli strains reveals a variety of virulence and novel antibiotic resistance plasmids
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- 作者：Liliana Losadaa ; liliana@swhr.org" class="auth_mail" title="E-mail the corresponding author ; Chitrita DebRoyb ; Diana Radunea ; Maria Kima ; Ravi Sankaa ; Lauren Brinkaca ; Subhashinie Kariyawasamb ; Daniel Sheltonc ; Pina M. Fratamicod ; Vivek Kapurb ; Peter C.H. Fenge ; peter.feng@fda.hhs.gov" class="auth_mail" title="E-mail the corresponding author
- 关键词：Genome sequencing ; STEC ; Plasmids ; Antibiotic resistance ; Virulence genes
- 刊名：Plasmid
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：83
- 期：Complete
- 页码：8-11
- 全文大小：351 K
文摘
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Many virulence and resistance genes in pathogenic E. coli are carried on plasmids.
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We sequenced plasmids from 26 Shiga toxin-producing and non-producing E. coli strains.
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We identified 39 plasmids that carried various virulence and putative virulence genes.
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We identified 8 plasmids that carried resistance to various antibiotics and some also had resistance genes for heavy metals.