Major infections, secondary cancers and autoimmune diseases occur in different clinical subsets of chronic lymphocytic leukaemia patients

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• 作者：Andrea Visentin^a ; ^b ; Silvia Imbergamo^a ; Carmela Gurrieri^a ; Federica Frezzato^a ; ^b ; Valentina Trimarco^a ; ^b ; Veronica Martini^a ; ^b ; Filippo Severin^a ; ^b ; Flavia Raggi^a ; ^b ; Edoardo Scomazzon^a ; Monica Facco^a ; ^b ; Francesco Piazza^a ; ^b ; Gianpietro Semenzato^a ; ^b ; ^{g.semenzato@unipd.it} ; Livio Trentin^a ; ^b ; ^{livio.trentin@unipd.it}
• 关键词：Chronic lymphocytic leukaemia ; Infections ; Secondary cancers ; Autoimmune diseases ; Hypogammaglobulinemia
• 刊名：European Journal of Cancer
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：72
• 期：Complete
• 页码：103-111
• 全文大小：792 K
• 卷排序：72

文摘

Major infections, secondary cancers and autoimmune diseases are the most common complications in patients with chronic lymphocytic leukaemia (CLL). We performed a single-centre retrospective study to investigate the prevalence of these complications in 795 patients with CLL. We identified clinical subsets of CLL patients characterised by an increased and different risk for developing specific kind of complications.