Unexpected side products in the tetramethylammonium fluoride–dimethylsulphoxide system
详细信息 查看全文
- 作者：Adams ; Dave J. ; Clark ; James H. ; McFarland ; Heather ; Nightingale ; David J.
- 关键词：Tetramethylammonium fluoride ; Dimethylsulphoxide ; Base catalysis ; Diphenylmethane ; Benzonitrile
- 刊名：Journal of Fluorine Chemistry
- 出版年：1999
- 出版时间：February 11, 1999
- 年：1999
- 卷：94
- 期：1
- 页码：51-55
- 全文大小：130 K
文摘
Reactions of chloro- and nitro-aromatics with low water content solutions of TMAF in DMSO can lead to complex product mixtures resulting from activation of DMSO by fluoride and the formation of DMSO-derived products. Also, the system has been shown to give hydrolysis products in addition to the well-known ethers and phenols, with carboxylic acids and benzamides being formed from the attempted fluorodenitration of substituted benzonitriles.