Distinct Subunit Domains Govern Synaptic Stability and Specificity of the Kainate Receptor
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- 作者：Christoph Straub1 ; 2 ; 6 ; Yoav Noam1 ; 2 ; 6 ; Toshihiro Nomura4 ; Miwako Yamasaki5 ; Dan Yan1 ; 2 ; Herman B. Fernandes4 ; Ping Zhang3 ; James R. Howe3 ; Masahiko Watanabe5 ; Anis Contractor4 ; Susumu Tomita1 ; 2 ; susumu.tomita@yale.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cell Reports
- 出版年：2016
- 出版时间：12 July 2016
- 年：2016
- 卷：16
- 期：2
- 页码：531-544
- 全文大小：5361 K
文摘
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The GluK2 cytoplasmic domain mediates synaptic stabilization
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Surface kainate receptor activity depends on GluK2 but not its cytoplasmic domain
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The extracellular domain of high-affinity GluK subunits mediates synaptic specificity
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Input-specific synaptic localization of kainate receptors is mediated by two mechanisms