Intracranial Inflammatory Myofibroblastic Tumor with Sarcomatous Local Recurrence

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• 作者：Yoen-Young Chuah¹ ; Tsewang Tashi² ; Cherng-Gueih Shy³ ; Jean-Shiunn Shyu⁴ ; Ming-Jeng Dong⁵ ; Er-Jung Hsueh⁶ ; ^{erjunghsueh@gmail.com" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Anaplastic lymphoma kinase ; Brain ; Inflammatory myofibroblastic tumor ; Recurrence ; Sarcomatous change
• 刊名：World Neurosurgery
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：93
• 期：Complete
• 页码：484.e1-484.e4
• 全文大小：961 K

文摘

A 20-year-old woman presented with a rare intracranial inflammatory myofibroblastic tumor (IMT) manifesting as headache and insomnia. Magnetic resonance imaging showed a tumorous lesion with heterogeneous enhancement at the right temporal lobe, as well as perifocal edema with midline shift. The tumor was totally resected with the margin free. Pathologic examination showed IMT with myofibroblastic cells admixed with collagen fibers. Sarcomatous change in morphology was observed in tumor recurrence within 7 months.

Conclusions

Surgical resection and whole brain radiation are recommended in patients with IMT.