- 作者：Joana Nunes ; joanacnunes@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Sara Nunes ; Mariano Veiga ; Mara Cortez ; Isabel Seifert
- 关键词：Analgesia ; Epidural ; Epidural analgesic techniques ; Infusion ; Obstetric analgesia ; Programmed intermittent bolus
- 刊名：Brazilian Journal of Anesthesiology (English Edition)
- 出版年：2016
- 出版时间：September-October 2016
- 年：2016
- 卷：66
- 期：5
- 页码：439-444
- 全文大小：711 K
Methods
In this study, 166 women with viable pregnancies were included. After an epidural loading dose of 10 mL with Ropivacaine 0.16% plus Sufentanil 10 μg, parturient were randomly assigned to one of three regimens: A – Ropivacaine 0.15% plus Sufentanil 0.2 μg/mL solution as continuous epidural infusion (5 mL/h, beginning immediately after the initial bolus); B – Ropivacaine 0.1% plus Sufentanil 0.2 μg/mL as programmed intermittent epidural bolus and C – Same solution as group A as programmed intermittent epidural bolus. PIEB regimens were programmed as 10 mL/h starting 60 min after the initial bolus. Rescue boluses of 5 mL of the same solution were administered, with the infusion pump. We evaluated maternal satisfaction using a verbal numeric scale from 0 to 10. We also evaluated adverse, maternal and neonatal outcomes.
Results
We analyzed 130 pregnants (A = 60; B = 33; C = 37). The median verbal numeric scale for maternal satisfaction was 8.8 in group A; 8.6 in group B and 8.6 in group C (p = 0.83). We found a higher caesarean delivery rate in group A (56.7%; p = 0.02). No differences in motor block, instrumental delivery rate and neonatal outcomes were observed.
Conclusions
Maintenance of epidural analgesia with programmed intermittent epidural bolus is associated with a reduced incidence of caesarean delivery with equally high maternal satisfaction and no adverse outcomes.