- 作者：Tevfik Guvenal ; Polat Dursun ; Pinar S. Hasdemir ; Merih Hanhan ; Suleyman Guven ; Hakan Yetimalar ; Behice P. Goksedef ; Derya K. Sakarya ; Arzu Doruk ; Mustafa C. Terek ; Bahadir Saatli ; Kadir Guzin ; Aydin Corakci ; Emek Deger ; Husnu Celik ; Ahmet Cetin ; Aydin Ozsaran ; Ay艧e Ozbakkaloglu ; Ali Kolusari ; Cetin Celik ; et al.
- 关键词：Borderline ; Ovarian tumor ; Lymphadenectomy ; Appendectomy ; Surgical staging
- 刊名：Gynecologic Oncology
- 出版年：December, 2013
- 年：2013
- 卷：131
- 期：3
- 页码：546-550
- 全文大小：342 K
Objective
The objectives of this study were to examine demographic and clinicopathologic characteristics and to determine the effects of primary surgery, surgical staging and the extensiveness of staging.Methods
In a retrospective Turkish multicenter study, 539 patients, from 14 institutions, with borderline ovarian tumors were investigated. Some of the demographic, clinical and surgical characteristics of the cases were evaluated. The effects of type of surgery, surgical staging; complete or incomplete staging on survival rates were calculated by using Kaplan-Meier method.
Results
The median age at diagnosis was 40 years (range 15-84) and 71.1% of patients were premenopausal. The most common histologic types were serous and mucinous. Majority of the staged cases were in Stage IA (73.5%). 242 patients underwent conservative surgery. Recurrence rates were significantly higher in conservative surgery group (8.3% vs. 3%). Of all patients in this study, 294 (54.5%) have undergone surgical staging procedures. Of the patients who underwent surgical staging, 228 (77.6%) had comprehensive staging including lymphadenectomy. Appendectomy was performed on 204 (37.8%) of the patients. The median follow-up time was 36 months (range 1-120 months). Five-year survival rate was 100% and median survival time was 120 months. Surgical staging, lymph node sampling or dissection and appendectomy didn't cause any difference on survival.
Conclusion
Comprehensive surgical staging, lymph node sampling or dissection and appendectomy are not beneficial in borderline ovarian tumors surgical management.