Spectral, electrochemical and molecular docking methods to get an understanding of supramolecular chemistry of sulfa drugs to biomolecules
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- 作者：N. Rajendiran ; drrajendiran@rediffmail.com" class="auth_mail" title="E-mail the corresponding author ; J. Thulasidhasan
- 关键词：Sulfapyridine ; Sulfadiazine ; Bovine serum albumin ; Fluorescence quenching ; Cyclic voltammetry ; Molecular docking
- 刊名：Journal of Molecular Liquids
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：212
- 期：Complete
- 页码：857-864
- 全文大小：1303 K
文摘
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Fluorescence intensities of BSA and adenine are decreased with sulfa drugs
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Compared to adenine more quenching is observed in the BSA with sulfa drugs
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Anodic electrode potential of BSA and adenine are decreased with sulfa drugs
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The interactions of SP with BSA/adenine are stronger than SD with BSA/adenine.
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SP contributes higher binding efficiency with BSA/adenine than SD.