A liquid chromatography - tandem mass spectrometry method to measure a selected panel of uremic retention solutes derived from endogenous and colonic microbial metabolism
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- 作者：Henriette de Loor
- 关键词：Ultra-performance liquid chromatography ; Tandem mass spectrometry ; Uremic retention solutes ; p-Cresyl sulfate ; Indoxyl sulfate ; Trimethylamine-N-oxide ; Phenylacetylglutamine
- 刊名：Analytica Chimica Acta
- 出版年：2016
- 出版时间：14 September 2016
- 年：2016
- 卷：936
- 期：Complete
- 页码：149-156
- 全文大小：331 K
文摘
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- <p id="p0010">Simultaneous quantification of fifteen relevant uremic retention solutes.p>
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- <p id="p0015">Comprehensive validation, highly sensitive and high through-put LC-MSMS method.p>
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- <p id="p0020">Comparison of different blood tubes.p>
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- <p id="p0025">Freeze-thaw stability.p>
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- <p id="p0030">Successful implementation in a clinical cohort of 488 patients with CKD.p>