Inhibition of In Vivo Tumor Angiogenesis and Growth Via Systemic Delivery of an Angiopoietin 2-Specific RNA Aptamer
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- 作者：Shiva Sarraf-Yazdi ; Jing Mi ; Benjamin J. Moeller ; Xilin Niu ; Rebekah R. White ; Christopher D. Kontos ; Bruce A. Sullenger ; Mark W. Dewhirst ; Bryan M. Clary
- 关键词：angiopoietin 2 ; Tie2 ; angiogenesis ; aptamer ; dorsal window chamber ; bioluminescence imaging
- 刊名：Journal of Surgical Research
- 出版年：2008
- 出版时间：1 May 2008
- 年：2008
- 卷：146
- 期：1
- 页码：16-23
- 全文大小：1326 K
文摘
This paper describes a novel and facile method for preparing the heavy metal MS (M = Ag, Cd and Pb) nanoparticles by bio-template of the squama inner coat of onion. Ag2S nanoparticles exhibit a diameter distribution in the range of 10–20 nm. CdS hollow nanoparticles exhibit a diameter distribution in the range of 85–100 nm. PbS nanoparticles with diameters in the range of 7–10 nm can also be prepared. Because of simple operation and mild conditions this method will have potential application in synthesizing nanoscale materials.