A combination of small molecules directly reprograms mouse fibroblasts into neural stem cells
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文摘

A combination of small molecules enable MEFs direct reprogrammed into NSCs state.

ciNSCs express markers similar to NSCs and expanded in vitro for several passages.

ciNSCs have a potential to differentiate into the neural lineages in vitro.

ciNSCs differentiated into mature neurons have a multipotent differentiation.

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