Biomarkers of angiogenesis as prognostic factors in myelodysplastic syndrome patients treated with hypomethylating agents
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- 作者：Chan Kyu Kima ; Dong Hoon Hana ; Young Seok Jia ; Min Sung Leea ; Chang Wook Mina ; Seong Kyu Park ; MD PhDa ; skpark@schmc.ac.kr" class="auth_mail" title="E-mail the corresponding author ; Se Hyung Kima ; Jina Yuna ; Hyun Jeung Kima ; Kyoung Ha Kimb ; Kyu Taek Leec ; Jong Ho Wonb ; Dae Sik Honga ; Hee Kyung Kimd
- 关键词：Myelodysplastic syndrome ; Angiogenesis ; Biomarker ; Hypomethylating agent
- 刊名：Leukemia Research
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：50
- 期：Complete
- 页码：21-28
- 全文大小：1363 K
文摘
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The role of angiogenesis in MDS has not been clearly revealed.
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Microvessel density (MVD) of RCUD was significantly lower than in other MDS types.
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MVD was closely associated with the responsiveness to hypomethylating agents in MDS.
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Angiogenesis related markers might be potentially prognostic factors for MDS.