Association of Cumulative Steroid Dose with Risk of Infection after Treatment for Severe Acute Graft-versus-Host Disease
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- 作者：Yayoi Matsumura-Kimoto1 ; 2 ; Yoshihiro Inamoto1 ; yinamoto@ncc.go.jp" class="auth_mail" title="E-mail the corresponding author ; Kinuko Tajima1 ; Akihisa Kawajiri1 ; Takashi Tanaka1 ; Tsuneaki Hirakawa1 ; Kazuko Ino1 ; Yu Asao1 ; Hiroyuki Tamogami1 ; Chika Kono1 ; Wataru Takeda1 ; Keiji Okinaka1 ; Shigeo Fuji1 ; Saiko Kurosawa1 ; Sung-Won Kim1 ; Ryuji Tanosaki3 ; Takuya Yamashita1 ; Takahiro Fukuda1
- 关键词：Graft-versus-host disease ; Fungal infection ; Hematopoietic cell transplantation ; Cytomegalovirus ; Adenovirus ; Steroid dose
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：22
- 期：6
- 页码：1102-1107
- 全文大小：564 K
文摘
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Invasive fungal disease was common (14%) after steroid therapy for severe graft-versus-host disease
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Viral disease was common (∼25%) after steroid therapy for severe graft-versus-host disease
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Gram-negative rod infection was common (20%) after steroid therapy for severe graft-versus-host disease
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Graft-versus-host disease within 26 days and low lymphocyte count correlated with risk of infection
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Cumulative steroid doses correlated with risks of fungal and viral diseases