Inverting the Topology of a Transmembrane Protein by Regulating the Translocation of the First Transmembrane Helix
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- 作者：Qiuyue Chen1 ; 2 ; Bray Denard1 ; 2 ; Ching-En Lee1 ; 2 ; Sungwon Han1 ; James S. Ye1 ; Jin Ye1 ; jin.ye@utsouthwestern.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Molecular Cell
- 出版年：2016
- 出版时间：18 August 2016
- 年：2016
- 卷：63
- 期：4
- 页码：567-578
- 全文大小：1722 K
文摘
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Ceramide alters translocation of TM4SF20 across ER membranes
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Alternative translocation changes the membrane topology and functions of TM4SF20
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TRAM2 mediates TM4SF20 translocation in the absence, but not presence, of ceramide