- 作者：H. Aloulou ; S. Triki ; A. Ahmed ; T. Kammoun ; M. Hachicha
- 关键词：Central insipid diabetes ; Children ; Treatment
- 刊名：Journal de Pediatrie et de Puericulture
- 出版年：2007
- 出版时间：November 2007
- 年：2007
- 卷：20
- 期：7
- 页码：289-294
- 全文大小：419 K
Patients and methods
The authors have studied retrospectively 6 cases of DIC hospitalised in the CHU Hédi Chaker of Sfax pediatrics service over a period of 19 years starting from the 1st of January 1987 though the 31st of December 2005. They have studied in our patients the clinic, biologic, neuroradiologic and etiologic particularities.
Results
During the period of study, the authors have studied 6 cases of DIC. The average age was of 7 years (1 year 9 months–13 years 3 months). The polyuropolydipsic syndrome represented the reason of consultation of all our patients. Hypotonic polyurie was constant with all children, it was about an average of 12,2 ml/kg/h. The test of hydrous restriction coupled with the Minirin® test has allowed us to perform the diagnosis of the DIC in all cases. The etiologic analyses including a neuroradiologic imagery (IRM and/or cerebral scanner) has permitted to show an expansive process of the median line (germinome) with one patient, an growth of the pituitary stem one patient, the cerebral scanner has been done to 2 children and it was normal. A patient was lost before doing the imagery. The thoracic scanner realized for one patient presenting dyspnoea showed pulmonary emphysema with an interstitial syndrome in aid of a langherancienne histiocytose. The coetaneous biopsy made on another patient having presented cuteness lesions confirmed too the diagnosis of Histiocytose. The DIC is idiopathic with the two other patients. The evolution has been marked by the death in one case, a progressive aggravation dyspnoea with 1 patient; otherwise, it was favourable for the other patients.
Conclusion
The DIC is rare in the child, the historic clinic brutal making the diagnostic easy; it is not the case with the investigations permitting to discover an etiology that can unmask over a long period justifying a prolonged supervision.