Multivitamin/mineral supplements: Rationale and safety - A systematic review

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• 作者：Hans K. Biesalski ; M.D. ; Ph.D. ; ^{biesal@uni-hohenheim.de} ; Jana Tinz ; M.Sc.
• 关键词：Multivitamins ; Minerals ; Supplements ; Safety ; Long-term use ; Randomized controlled studies (RCTs)
• 刊名：Nutrition
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：33
• 期：Complete
• 页码：76-82
• 全文大小：263 K
• 卷排序：33

文摘

Multivitamin/mineral supplements (MVM) use is common in the general population, which raises questions regarding the safety of long-term use of these supplements. MVM use within the range of the dietary reference intake will not result in excess intake, even when including the impact of food and fortified food, and does not increase mortality. Despite a balanced and overall healthy diet, micronutrient gaps may occur from time to time. An MVM can help to improve the nutrient supply and overcome problems of inadequacy without concern for its long-term safety. MVM are safe for long-term use (more than 10 y) as documented in a recent clinical trial. An increasing number of individuals take MVM to maintain good health and to be protected from different diseases.