Spectroscopic, calorimetric, cyclic voltammetric and molecular modeling studies of new methylene blue-polyadenylic acid interaction and comparison to thionine and toluidine blue O: Understanding self-structure formation by planar dyes
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- 作者：Puja Paula ; b ; Soumya Sundar Matib ; 1 ; Subhash Chandra Bhattacharyab ; Gopinatha Suresh Kumara ; gskumar@iicb.res.in" class="auth_mail" title="E-mail the corresponding author ; gsk.iicb@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Phenothiazinium dyes ; Poly(A) ; Thermodynamics ; Self-structure ; Modeling
- 刊名：Dyes and Pigments
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：136
- 期：Complete
- 页码：205-218
- 全文大小：2499 K
文摘
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Thionine was a better binder to poly(A) than toluidine blue and new methylene blue.
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Small heat capacity changes indicated hydrophobic contribution in the binding.
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The binding induced secondary structure formation in single stranded poly(A).
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Cyclic voltammetric confirmed strong association between the dyes and poly(A).
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Molecular modeling revealed the actual orientation of dye molecules inside poly(A).