Nanoemulsion-templated polylelectrolyte multifunctional nanocapsules for DNA entrapment and bioimaging
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- 作者：Urszula Bazylińskaa ; urszula.bazylinska@pwr.edu.pl" class="auth_mail" title="E-mail the corresponding author ; Jolanta Saczkob
- 关键词：Oil-core nanocarriers ; IR-780 cyanine ; Cationic gemini-type surfactants ; Human cancer cell lines ; Chitosan ; Layer-by-layer approach
- 刊名：Colloids and Surfaces B: Biointerfaces
- 出版年：2016
- 出版时间：1 January 2016
- 年：2016
- 卷：137
- 期：Complete
- 页码：191-202
- 全文大小：2759 K
文摘
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Model DNA molecules were deposited on the nanoemulsion core loaded by IR-780 indocyanine.
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The nanoemulsions were stabilized by quaternary ammonium gemini surfactants.
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Ternary phase diagrams of the surfactant–oil–water systems were determined by titration method.
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Multifunctional nanocapsules with CHIT shell were obtained by layer-by-layer approach.
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Biological response of the MCF-7/WT, A549 and MEWO cells was evaluated.