An improvement of surfactin production by B. subtilis BBG131 using design of experiments in microbioreactors and continuous process in bubbleless membrane bioreactor
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- 作者：Luiz Fernando Motta Dos Santosa ; b ; Franç ; ois Couttea ; francois.coutte@polytech-lille.fr" class="auth_mail" title="E-mail the corresponding author ; Rozenn Ravalleca ; Pascal Dhulstera ; Lucie Tournier-Couturierb ; Philippe Jacquesa
- 关键词：B. subtilis ; Surfactin ; Medium optimization ; Design of experiments ; Response surface methodology
- 刊名：Bioresource Technology
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：218
- 期：Complete
- 页码：944-952
- 全文大小：1399 K
文摘
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Highthroughput approach and DoE to optimize surfactin production by B. subtilis.
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Highlight the medium limiting element impacting surfactin specific production.
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Investigate optimized media for continuous production of surfactin in BMBR.