Gut-Resident Lactobacillus Abundance Associates with IDO1 Inhibition and Th17 Dynamics in SIV-Infected Macaques
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- 作者：Ivan Vujkovic-Cvijin1 ; Louise A. Swainson1 ; Simon N. Chu1 ; 2 ; Alexandra M. Ortiz3 ; Clark A. Santee4 ; Annalise Petriello1 ; Richard M. Dunham1 ; 10 ; Douglas W. Fadrosh4 ; Din L. Lin4 ; Ali A. Faruqi4 ; Yong Huang5 ; Cristian Apetrei6 ; Ivona Pandrea6 ; Frederick M. Hecht7 ; Christopher D. Pilcher7 ; Nichole R. Klatt8 ; Jason M. Brenchley3 ; Susan V. Lynch4 ; 9 ; susan.lynch@ucsf.edu" class="auth_mail" title="E-mail the corresponding author ; Joseph M. McCune1 ; 9 ; mike.mccune@ucsf.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cell Reports
- 出版年：2015
- 出版时间：24 November 2015
- 年：2015
- 卷：13
- 期：8
- 页码：1589-1597
- 全文大小：1225 K
文摘
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IDO1 activity correlates with loss of barrier-promoting Th17 cells in SIV infection
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Abundance of gut-resident Lactobacillus correlates with IDO1 activity and Th17 cells
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Probiotics containing Lactobacillus reduce IDO1 activity in SIV-infected macaques