Reduced regional systolic function evolved compacted segments in noncompaction

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• 作者：Giovanni Fazio ; Giuseppina Novo ; Luciana D'angelo ; Monica Lunetta ; Loredana Sutera ; Gabriele di Gesaro ; Giuseppe Indovina ; Filippo Ferrara ; Salvatore Novo
• 关键词：Noncompaction ; Systolic dysfunction ; Segmental alterations ; Delay enhancement ; Scintigraphy
• 刊名：International Journal of Cardiology
• 出版年：2010
• 出版时间：3 September 2010
• 年：2010
• 卷：143
• 期：3
• 页码：442
• 全文大小：44 K

文摘

In a recent report about noncompaction Nemes et al. reported that systolic left ventricular (LV) dysfunction assessed using the wall motion score during 2D echocardiography in noncompaction is not confined to noncompacted LV segments.

These results confirmed some published reports of our group. Recently we analyzed a population of 238 patients affected by noncompaction, and demonstrated that the number of noncompacted segment is uncorrelated with the degree of systolic dysfunction. It is an attractive hypothesis that the systolic dysfunction could be depend on the fibrosis of the left ventricle, itself a consequence of microcirculatory dysfunction, which has been confirmed by reports that describe microvascular dysfunction using myocardial scintigraphy.