Gene Editing in Stem Cells Hits the Target

详细信息    查看全文

• 作者：Ho W. Kim¹ ; Clive  ; Niels Svendsen¹ ; ^{clive.svendsen@cshs.org"" rel=""nofollow}
• 刊名：Cell Stem Cell
• 出版年：2011
• 出版时间：5 August 2011
• 年：2011
• 卷：9
• 期：2
• 页码：93-94
• 全文大小：70 K

文摘

Two recent reports describe promising, highly efficient methods to modify genes in pluripotent stem cells using zinc finger nuclease (ZFN)-mediated (Soldner et al., 2011) or helper-dependent adenovirus (HDAdV)-mediated (Liu et al., 2011b) gene modification. These technical developments will have far ranging effects on the rapidly growing field of regenerative medicine.