Low putamen activity associated with poor reward sensitivity in childhood chronic fatigue syndrome

详细信息    查看全文

• 作者：Kei Mizuno ; Ph.D.^a ; ^b ; ^c ; ^e ; ^{keimizuno@riken.jp} ; Junko Kawatani^f ; Kanako Tajima^a ; ^b ; Akihiro T. Sasaki^a ; ^b ; ^d ; ^e ; Tetsuya Yoneda^h ; Masanori Komiⁱ ; ^j ; Toshinori Hirai^k ; ^l ; Akemi Tomoda^m ; Takako Joudoi^g ; Yasuyoshi Watanabe^a ; ^b ; ^d ; ^e
• 关键词：Childhood chronic fatigue syndrome ; Dopamine ; fMRI ; Motivation ; Putamen ; Reward sensitivity
• 刊名：NeuroImage: Clinical
• 出版年：2016
• 出版时间：2016
• 年：2016
• 卷：12
• 期：Complete
• 页码：600-606
• 全文大小：710 K
• 卷排序：12

文摘

Childhood chronic fatigue syndrome (CCFS) may have low neural reward processing. Activity in the putamen was specifically decreased in low monetary reward. Reduced activity of putamen was correlated with fatigue and reward from learning. Low activity of the putamen is associated with poor reward sensitivity. Decreased neural reward processing suggests dopamine dysfunction in CCFS patients.