- 作者：Alberto Carrillo ; José ; Marí ; a Enrí ; quez-Navascué ; s ; josemaria.enriqueznavascues@osakidetza.net" class="auth_mail" title="E-mail the corresponding author ; Araceli Rodrí ; guez ; Carlos Placer ; José ; Antonio Mú ; gica ; Yolanda Saralegui ; Ander Timoteo ; Nerea Borda
- 关键词：Rectal neoplasm ; Anterior resection of rectum ; Anterior resection syndrome ; LARS scale ; Functional results
- 刊名：Cirugía Española (English Edition)
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：94
- 期：3
- 页码：137-143
- 全文大小：381 K
Methods
All operated patients with anterior resection for rectal cancer between October 2007 and February 2014, with curative intention and at least one year of functionality, were sent a LARS questionnaire. The variables studied were age sex, time elapsed since surgery, type of surgical approach, type of anastomosis, derivative ileostomy, postoperative pelvic complication, and radiotherapy regimen.
Results
Out of 195 patients, 136 (70%) responded, and 132 responded properly. A total of 47% of the patients presented “severe” LARS and 34% did not develop quantifiable ARS. Quality of life was worse in the highest LARS scores (P=.002). In the univariate analysis, total mesorectal excision, long radiotherapy regimen and derivative stoma were associated to “severe” LARS and the use of a reservoir was associated with minor LARS. In multivariate analysis only the type of resection (P<.001) and the use of a reservoir (P=.002) were individual factors related to LARS.
Conclusions
Half of the operated patients presented high LARS score and only a third did not provide a quantifiable ARS. The overall perception of quality of life was significantly worse in patients with more severe LARS. The absence of the rectum (total mesorectal excision) and the type of anastomosis were the main factors associated with the LARS score.